Cardholders are assigned a Time Profile to determine when the cardholders can gain access. The default All User group gives a cardholder access at the door/doors all day, seven days a week). For new time profiles you will first need to create a time schedule - unless you will use the default 'All Time' group.
Note: Multiple controllers can be managed from a single app, but only on a one-to-one basis - (because each controller has its own database). For this reason, a time profile will only contain the reader(s) for a single controller (you cannot setup a time profile that includes readers from multiple controllers).